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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EOMES All Species: 7.58
Human Site: S52 Identified Species: 13.89
UniProt: O95936 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95936 NP_005433.2 686 72732 S52 K L D L D K A S K K F S G S L
Chimpanzee Pan troglodytes XP_001165803 690 73333 S52 K L D L D K A S K K F S G S L
Rhesus Macaque Macaca mulatta XP_001093085 737 80029 A68 L P E R L L A A S P I G G S P
Dog Lupus familis XP_850738 688 72729 P52 R L D L D K A P K K F P G S L
Cat Felis silvestris
Mouse Mus musculus O54839 707 74783 S52 L L P G A A P S P Q R L D L D
Rat Rattus norvegicus XP_001061749 663 70857 P52 S L L P G A A P S P Q R L D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514679 386 42515
Chicken Gallus gallus XP_426003 399 44936
Frog Xenopus laevis P79944 692 75925 D51 T F Y P L T G D P S S A V H S
Zebra Danio Brachydanio rerio NP_571754 661 71990 S51 R T D S E Q S S G A K K F L M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24432 972 102538 N74 S N N N T N S N T N N T N N L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19691 423 46979
Sea Urchin Strong. purpuratus XP_791266 946 105128 L162 Q S N L P Q Y L L N T N C T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 80 96.5 N.A. 87.5 81.6 N.A. 25.6 52.4 62.1 57.5 N.A. 22.9 N.A. 24.7 23.6
Protein Similarity: 100 99.1 82.9 96.9 N.A. 89.3 83.9 N.A. 33.5 54.5 70.5 68.9 N.A. 35.2 N.A. 34.9 37.9
P-Site Identity: 100 100 20 80 N.A. 13.3 20 N.A. 0 0 0 13.3 N.A. 6.6 N.A. 0 13.3
P-Site Similarity: 100 100 33.3 86.6 N.A. 20 20 N.A. 0 0 6.6 46.6 N.A. 40 N.A. 0 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 16 39 8 0 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 31 0 24 0 0 8 0 0 0 0 8 8 8 % D
% Glu: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 24 0 8 0 0 % F
% Gly: 0 0 0 8 8 0 8 0 8 0 0 8 31 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 16 0 0 0 0 24 0 0 24 24 8 8 0 0 0 % K
% Leu: 16 39 8 31 16 8 0 8 8 0 0 8 8 16 47 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 8 16 8 0 8 0 8 0 16 8 8 8 8 0 % N
% Pro: 0 8 8 16 8 0 8 16 16 16 0 8 0 0 8 % P
% Gln: 8 0 0 0 0 16 0 0 0 8 8 0 0 0 0 % Q
% Arg: 16 0 0 8 0 0 0 0 0 0 8 8 0 0 0 % R
% Ser: 16 8 0 8 0 0 16 31 16 8 8 16 0 31 8 % S
% Thr: 8 8 0 0 8 8 0 0 8 0 8 8 0 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _